![]() Hypocretin keeps the brain alert and body awake while preventing rapid eye movement (REM) sleep. Without hypocretin, the body can’t properly control sleep functions. Type 1 narcolepsy is caused by a lack of a brain chemical called hypocretin. In some people, fear and stress can also trigger cataplexy. These episodes can last a few seconds to a few minutes and are often brought on by surprise, laughter, or other emotional responses - usually positive emotions. A person may experience their jaw dropping, a knee buckling while walking, or a sudden weakness of the arms. ![]() At times, not all the muscles are affected. Sometimes the muscles only stop working on one side of the body.ĭuring a cataplectic episode, a person’s muscles suddenly go slack while they remain fully awake and aware, almost like they’re paralyzed. The muscle slackness can be as subtle as a droopy eye, or it can be more noticeable, like slumping over in their seat. Nighttime sleep disruptions - Insomnia can worsen EDSĬataplexy looks different in different people. ![]()
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